![]() ![]() RINVOQ may increase your risk of certain cancers, including lymphoma, skin, and lung cancer, as these can happen. ![]() ![]() Increased risk of death in people 50 years and older with at least 1 heart disease (cardiovascular) risk factor. ![]() Some people have died from these infections. Serious infections have happened while taking RINVOQ, including tuberculosis (TB) and infections caused by bacteria, fungi, or viruses that can spread throughout the body. RINVOQ can lower your ability to fight infections. RINVOQ may cause serious side effects, including:.Other specific adverse reactions reported in atopic dermatitis patients included eczema herpeticum/Kaposi's varicelliform eruption. Overall, the safety profile observed in patients with atopic dermatitis treated with RINVOQ 15 mg or 30 mg was similar to the safety profile observed in patients with rheumatoid arthritis.In all three studies, a significant improvement in itch (Worst Pruritus NRS ≥4) was observed as early as week one, compared to placebo.Worst Pruritus NRS ≥4 is defined as the proportion of subjects achieving an improvement in Worst Pruritus Numerical Rating Scale (NRS) ≥4 for subjects with Worst Pruritus NRS score ≥4 at baseline. VIGA-AD 0/1 is defined as a validated Investigator Global Assessment for Atopic Dermatitis of clear or almost clear (0/1) with at least two grades of reduction from baseline. EASI 90 and 100 are defined as at least 90 percent or 100 percent reduction in Eczema Area and Severity Index. **Endpoint not controlled for multiplicity.ĮASI 75 is defined as at least a 75 percent reduction in Eczema Area and Severity Index. *Co-primary endpoints were EASI 75 and vIGA-AD 0/1 at week 16. RINVOQ COPAY CARD SKIN
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